RFP 27-27 Benchtop NMR Spectrometer

Description: 1.0 Introduction The University of Southern Mississippi (USM) is looking to procure a Benchtop NMR Spectrometer. 2.0 Specifications 2.1 GENERAL PERFORMANCE SPECIFICATIONS The Benchtop NMR Spectrometer must be compatible with the Bruker TopSpin software platform and able to utilize the same software environment and workflow based on the requirements specified below. 2.2 REQUIREMENTS The following specifications are to ensure that the Benchtop NMR Spectrometer will perform the tasks necessary to satisfy the project's objectives. Any deviation from the following specifications must be explained and justified. Bidder shall meet or exceed the following specifications: x The benchtop NMR system must meet the department's requirement for direct software compatibility and workflow continuity with the existing Bruker 400 MHz NMR spectrometer through the Bruker TopSpin software platform. x The benchtop NMR system must provide the following specifications: o Cryogen-free, temperature-controlled permanent magnet at an operating proton frequency of 80 MHz, no liquid nitrogen or helium, no water cooling or additional venting required o Dimensions: ~50/ 70/ 60 cm (H/ W/ D), weight: ~94 kg o Power consumption < 300 W, power: 100-240 V, 50-60 Hz o Receiver bandwidth up to 1 MHz, RF shapes: 14-bit resolution, RF time resolution: 12.5 ns o Ethernet connections: 1 to PC or network, 1 to optional accessories o 1 Trigger Input: Control of running experiments (pulse program) via external TTL trigger signal in real-time o 1 Trigger Output: Control external units via TTL trigger signal in realtime by running experiments (pulse programs) o Dedicated education protocols, acquisition and analysis software included, automated shim routine o TopSpin pulse program library included, Non-Uniform Sampling (NUS) possible o Fourier standard shim sample included o Fourier standard line shape sample included o Fourier 80 system to be used in a temperature-regulated room of +18 °C to +28 °C with typical temperature variations of max. ±1.5 °C o Fourier accessory case to include: ▪ 2 Fourier sample tube holders for 7 inch long NMR standard tubes with an outer diameter of 5 mm (Z170760) ▪ 1 Fourier cleaning kit to be used in case of tube breakage, to remove broken glass and spill safely from the probe (H176417) ▪ 100 economy tubes for routine NMR, 5 mm outer diameter, 7 inch length, wall 0.38 mm, camber 60 um, including Bruker caps without holes with code (Z172600) ▪ USB-stick including Fourier documentation in electronic format (1867248) ▪ 2 Backup fuses, 5x20 mm, 6.3 A (1801717) o 1H/13C double channel probe for standard 5 mm diameter, 7 inch long NMR tubes ▪ Digital Lock: external (no deuterated solvents needed) ▪ Sensitivity: 1H > 160:1 for 1% ethyl benzene ▪ RF power 1H: 5W, 13C: 20 W ▪ Experiments e.g.: 1H: 1D, 1D with solvent suppression,1D selective excitation, T1, T2, reaction monitoring, 1H 2D: COSY, JRES, 13C: 1D (with NOE and decoupling), DEPT45, DEPT90, DEPT135, ATP, 13C-1H 2D: HMBC, HSQC, HMQC, HETCOR o Bench PC with Touchscreen ▪ Workstation to be placed between screen and screen base ▪ Monitor with touchscreen (23'') ▪ 1920 x 1080 at 60 Hz ▪ At least Windows 10 ▪ Intel® Core™ i3 Processor ▪ 16 GB SDRAM ▪ 256 GB SSD o Basic acquisition and processing license package for the use on a Fourier 80 benchtop system (ACA), incl.: ▪ GoScan acquisition license, incl.: x Straightforward entry-level Software for data acquisition x Optimized for mouse and touch screen operation x Configurable library of experiments x Import of TopSpin parameter sets possible x Combination of several experiments into one push-button x Overview over results and direct link to TopSpin for processing and analysis x Data can be exported automatically to an additional storage (hard disk or external server or USB stick) ▪ TopSpin 4 acquisition and processing license, incl.: x NMR data acquisition (arbitrary dimensions) and processing (1D-6D) x NMRGuide - a collection of theoretical information and practical tips around NMR for training of users in use of 1D and 2D experiments with NMR literature library x IconNMR x Processing of non-uniformly sampled (NUS) data for 2D spectra x Spectra analysis, including automated integration and deconvolution of NMR spectra x Workflow automation: serial processing, AU programs, python scripts x NMRSIM and DAISY for experiment simulation and 1D and 2D spectra prediction x Relaxation analysis (T1/T2) x TopSpin integrated structure editor o Full installation at customer site performed by trained Bruker Service engineer: ▪ Unpack and place the system on a stable vibration-free desk ▪ Check that no magnetic parts as well as high current power lines are close to the system ▪ Plug in power supply and switch on the system ▪ Wait for the magnet to stabilize its temperature ▪ Shimming the magnet ▪ Configure the system ▪ Set the lock ▪ Software introduction and basic training ▪ Acceptance protocol o Pulsed Field Gradient ▪ Probe equipped with an one-axis gradient ▪ Full linear gradient ▪ Gradient: 5 A max. current ▪ Gradient power: >0.25 T/m (> 25 G/ cm) ▪ Gradient shape resolution: 18 bit ▪ Gradient time resolution: 10 us 2.4 CUSTOMER SUPPORT The vendor should be willing to help The University of Southern Mississippi resolve any technical issues associated with the system, not only in the warranty period but also out of the warranty period with a reasonable service fee and leading time. It is preferred that the vendor can provide technical service through remote access and/or on-site technical support. 2.5 SAFETY Safety should be well weighted in machine design, engineering delivery and user interface communication. Safety measures and appropriate designs for any moving parts. Emergency stop systems should be available. 2.6 WARRANTY Bidder warrants that the machinery shall be free from defects in material and workmanship under normal use and service with obligation to repair or replace any parts, which are proven defective, within one year from delivery. 2.7 DELIVERY Vendor should quote the lead time required for delivery of the quoted equipment. Quoted prices should be F.O.B. Destination Freight Allowed. 4.0 Points of Contact For questions, contact the Buyer listed on the Bid Coversheet at: bids@usm.edu 5.0 Submission Instructions to Bidders One (1) signed original, two (2) copies, and one (1) portable virus/malware free electronic version (USB jump drive) of the sealed bid response (if electronic copy is not included, USM reserves the right to request an electronic copy of the exact bid reponse prior to review of the bid), subject to the conditions made a part hereof, will be received by established date/ time in the USM Procurement and Contract Services office, as indicated in the General Terms, Conditions, and Instructions to Bidders described herein. It is the responsibility of the respondent to ensure that the proposal package arrives in the Procurement and Contract Services Office. Each bid must be submitted in a sealed envelope bearing on the outside the name "Bid 27-27 Benchtop NMR Spectrometer," the name of the Vendor, and the opening date specified on the coversheet. The proposal should be addressed as follows: For regular mail: The University of Southern Mississippi Attn: Amber Floyd, Buyer 118 College Drive, Box 5003 Hattiesburg, MS 39406 Bid #27-27 For FedEx, UPS, or other express couriers: The University of Southern Mississippi Attn: Amber Floyd, Buyer 2609 W. 4th Street Hattiesburg, MS 39401 Bid #27-27 Hand-carried responses should be brought to: The University of Southern Mississippi Attn: Amber Floyd, Buyer 214 Bond Hall Hattiesburg, MS 39406 Bid #27-27 As an alternative to traditional sealed proposals in envelopes, the University of Southern Mississippi is capable of receiving electronic bid responses. While this option is available, it is not required and the University asks that all potential respondents keep in mind that with any electronic system there could be delays or glitches with the submission process; therefore the University highly encourages traditional sealed responses which are either mailed or submitted in person. Additionally, the University will not be responsible for issues with attempted submissions of bids using the electronic method. Please note that emailed bids will not be accepted. Should a vendor choose to submit their response electronically, suppliers will need to register on the State of Mississippi procurement portal and use the Procurement Opportunities area to locate and submit responses. Any bid may be withdrawn prior to scheduled time for the opening of bids or authorized postponement thereof. Any bid received after the time and date specified will not be considered. The University of Southern Mississippi reserves the right to accept or reject any or all bids and to waive any formalities. The University of Southern Mississippi reserves the right to accept or reject optional line items included in the bid response. Vendors are responsible for examining all specifications, terms, conditions, and instructions of this request. Failure to do so will be at Vendor's risk. In order to ensure all interested bidders receive any addenda that may be issued, proposers must email their intent to propose using the Intent to Bid link on the USM Bid Calendar under Bid 27-27 prior to the deadline to submit.