Description: Provide obtain DNA methylation profiling and epigenetic age analysis for 320 previously extracted murine DNA samples using the Mammal320K methylation array and established horvath epigenetic clock methodologies.
Federal · MD, US
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The National Institutes of Health's National Institute on Aging seeks DNA methylation profiling and epigenetic age analysis for 320 previously extracted murine DNA samples. The work covers 80 blood-derived and 240 tissue-derived samples and uses the Mammal320K methylation array and Horvath epigenetic clock methodologies, including bisulfite conversion, array processing, scanning, quality control, and bioinformatic analysis. The notice is a non-competitive combined synopsis/solicitation, with deliverables including raw data, quality-control documentation, biological-age estimates, and comparative analyses for normoxic control, intermittent hypoxia, and intermittent hyperoxia conditions.
Decision makers connected to this RFP from National Institutes of Health NIA.
