NOI; non-competitive combined synopsis solicitatio

Description: The National Institutes of Health's National Institute on Aging seeks DNA methylation profiling and epigenetic age analysis for 320 previously extracted murine DNA samples. The work covers 80 blood-derived and 240 tissue-derived samples and uses the Mammal320K methylation array and Horvath epigenetic clock methodologies, including bisulfite conversion, array processing, scanning, quality control, and bioinformatic analysis. The notice is a non-competitive combined synopsis/solicitation, with deliverables including raw data, quality-control documentation, biological-age estimates, and comparative analyses for normoxic control, intermittent hypoxia, and intermittent hyperoxia conditions.