TIDAL: Target-Induced Droplet Assembly of Ligands

Description: This active special notice from the Department of Energy presents TIDAL, a technology developed by Los Alamos National Laboratory that converts nanobodies into programmable, protein-only materials. The technology uses target-induced liquid-liquid phase separation to form dynamic protein droplets with potential applications in protein purification, drug delivery, diagnostics, and biotechnology. It is a technology-licensing notice rather than a grant program or a call for external services to develop the technology.