Summary
The National Institute of Allergy and Infectious Diseases (NIAID) is soliciting applications under the Clinical Trials in Organ Transplantation in Children and Adults (CTOT-CA) program to support multicenter clinical trials and mechanistic studies to improve organ transplantation outcomes. The program will fund trials across heart, lung, kidney, liver, and intestinal transplantation and may support non-hematopoietic cellular replacement therapies, vascularized composite tissue transplantation, and adjunctive cell therapies. NIAID estimates $11,280,000 in total funding to be awarded to multiple recipients under a cooperative agreement mechanism.