Department of Health and Human Services RFPs

Technology InteGrator and AcceleratoR (TIGAR)

ARPA-H has issued an Innovative Solutions Opening (ISO) solicitation (ARPA-H-SOL-26-144) under the Technology InteGrator and AcceleratoR (TIGAR) program seeking high-risk, high-impact biopreservation technologies.

Office of Biomedical Advanced Research and Development Authority (BARDA) Broad Agency Announcement (BAA)

Advanced research and development (R&D) of medical countermeasures (MCMs) for chemical, biological, radiological, and nuclear (CBRN) agents, pandemic influenza, and emerging infectious diseases.

ORR Process and Technology Modernization (OPTM) Platform and Home Studies/Post-Release Services (HS/PRS) Application Enhancement and Support RFP

This active SAM.gov Special Notice concerns HHS's intended sole-source bridge contract, solicitation 7571MN26Q00111, for continued operation, maintenance, enhancement, and Tier 3 support of the ORR Process and Technology Modernization (OPTM) Platform and the Home Studies/Post-Release Services (HS/PRS) applications.

Specialized Legal Recruiting (Request for Proposal)

Specialized legal recruiting.

Auto Droplet Generator

The National Institute of Diabetes and Digestive and Kidney Diseases seeks an Auto Droplet Generator to automate droplet generation for droplet digital PCR workflows involving pancreatic islets and islet organoids.

Handshake Subscription

The U.S. Department of Health and Human Services is soliciting continued access to the Handshake Talent Engagement Suite for CMS's targeted recruitment and outreach efforts.

Proactive Health Office (PHO) Mission Office Innovative Solutions Opening (ISO) (ARPA-H-SOL-24-106)

ORR Process and Technology Modernization (OPTM) Platform and Home Studies/Post-Release Services (HS/PRS) Application Enhancement and Support

This active SAM.gov Special Notice concerns HHS's intended sole-source bridge contract, solicitation 7571MN26Q00111, for continued operation, maintenance, enhancement, and Tier 3 support of the ORR Process and Technology Modernization (OPTM) Platform and the Home Studies/Post-Release Services (HS/PRS) applications.

UNifying Imaging with QUantum Entanglement (UNIQUE) Proposers' Day

The Advanced Research Projects Agency for Health (ARPA-H), a sub-agency of the U.S. Department of Health and Human Services under NIH, issued Special Notice ARPA-H-SN-26-162 announcing a Proposers' Day on October 15, 2026 for the newly approved UNIFYING Imaging with QUantum Entanglement (UNIQUE) program.

ARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions Opening

Comprehensive Organ System Modeling in Outer Space (COSMOS) Initiative aims to definitively prove or disprove if exposure to microgravity in Low Earth Orbit (LEO) truly accelerates tissue aging across brain, cardiac, uterine, and kidney tissue types and across several adult age brackets.

Auto Droplet Generator RFP

The National Institute of Diabetes and Digestive and Kidney Diseases seeks an Auto Droplet Generator to automate droplet generation for droplet digital PCR workflows involving pancreatic islets and islet organoids.