Summary
The Advanced Research Projects Agency for Health (ARPA-H) issued Solicitation ARPA-H-SOL-26-155 (IGoR) to create an AI-enabled interoperable research ecosystem that accelerates biomedical discovery by combining mechanistic disease models, an AI orchestration layer, standardized experimental protocols, and a distributed lab marketplace. ARPA-H anticipates awarding contracts to multidisciplinary teams to develop the four program components over a multi-phase, five-year initiative and expects significant interest. The solicitation requires submission of a Solution Summary (required step) followed by invitation/encouragement to submit a Full Proposal.