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The AIR program will consist of an initial two-year Phase 1 and a three-year Phase 2 for a total of five (5) years. At the end of Phase 1, only some teams will be selected to continue as performers, based on performance with respect to metrics and milestones. Meeting metrics and milestones does not guarantee program continuation. Technical Area 1: Autonomous Endovascular Robotics: Technical Area 1 consists of two (2) independent sub-areas: TA1-A for endovascular robotic systems, and TA1-B for the development of an in silico simulation environment and the creation of a medical imaging data set needed to train the robots and the environments, including but not limited to fluoroscopic videos of endovascular procedures (neurovascular preferred) and CT angiograms. The results of TA1-B will support TA1-A development, validation, and regulatory approval efforts. See attached file.
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ARPA-H posted the AIR Innovative Solutions Opening (ISO) ARPA-H‑SOL‑26‑146 soliciting proposals to advance autonomous interventions and robotics research under the AIR program. The solicitation includes an Amendment #01 that updates the Solution Summary due date to 20 January 2026 at 5:00 PM ET and the Full Proposal due date to 18 March 2026 at 5:00 PM ET. Program materials and submission/teaming links are provided on the ARPA‑H program pages and via the SAM.gov attachments.
Posted Date
Nov 20, 2025
Due Date
Mar 18, 2026
Release: Nov 20, 2025
Close: Mar 18, 2026
ARPA-H posted the AIR Innovative Solutions Opening (ISO) ARPA-H‑SOL‑26‑146 soliciting proposals to advance autonomous interventions and robotics research under the AIR program. The solicitation includes an Amendment #01 that updates the Solution Summary due date to 20 January 2026 at 5:00 PM ET and the Full Proposal due date to 18 March 2026 at 5:00 PM ET. Program materials and submission/teaming links are provided on the ARPA‑H program pages and via the SAM.gov attachments.
AvailableProvide FY26 FDA Broad Agency Announcement (BAA) for Advanced Research and Development of Regulatory Science.
Posted Date
Nov 21, 2025
Due Date
Feb 24, 2026
Release: Nov 21, 2025
Close: Feb 24, 2026
Provide FY26 FDA Broad Agency Announcement (BAA) for Advanced Research and Development of Regulatory Science.
AvailableResearch institute for the behavioral and social sciences (ari) broad agency announcement for basic, applied, and advanced scientific research.
Posted Date
May 1, 2023
Due Date
May 1, 2028
Release: May 1, 2023
Close: May 1, 2028
Research institute for the behavioral and social sciences (ari) broad agency announcement for basic, applied, and advanced scientific research.
AvailableThe FDA (HHS) issued a FY26 Broad Agency Announcement seeking proposals for advanced research and development in regulatory science to develop tools, standards, and approaches for assessing safety, efficacy, quality, and performance of FDA-regulated products. Areas of interest include New Approach Methodologies, advanced manufacturing, analytic and computational methods, biomarkers, clinical outcome assessment, predictive toxicology, and methods to assess real-world data as real-world evidence. The BAA will consider proposals for multi-year projects and encourages submission by February 24, 2026 for FY26 consideration.
Posted Date
Nov 21, 2025
Due Date
Feb 25, 2026
Release: Nov 21, 2025
Close: Feb 25, 2026
The FDA (HHS) issued a FY26 Broad Agency Announcement seeking proposals for advanced research and development in regulatory science to develop tools, standards, and approaches for assessing safety, efficacy, quality, and performance of FDA-regulated products. Areas of interest include New Approach Methodologies, advanced manufacturing, analytic and computational methods, biomarkers, clinical outcome assessment, predictive toxicology, and methods to assess real-world data as real-world evidence. The BAA will consider proposals for multi-year projects and encourages submission by February 24, 2026 for FY26 consideration.
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